Laboratory of Bioinformatics Analyses for Genomics and Metabolism
Dear users, We have decided to retire our old web tools MICHECK and AMIGene. Those tools have not been maintained for several years and are no longer useful as they (and many others) are integrated in MicroScope. We will proceed
PPanGGOLiN (Gautreau et al. 2020) is a software suite used to create and manipulate prokaryotic pangenomes from a set of either genomic DNA sequences or provided genome annotations. It is designed to scale up to tens of thousands of genomes.
ASMC method (Active Sites Modeling and Clustering) is a novel unsupervised method to classify sequences using structural information of protein pockets. The method predicts functional amino-acids by proposing active site SDP residues (Specificity Determining Position) and active site CP residues
GROOLS (Genomic Rule Oriented Object Logic System) is a bioinformatics software that helps biologists in the evaluation of genome functional annotation through biological processes like metabolic pathways. GROOLS is an expert system that uses paraconsistent logic. It evaluates the completeness
We developed a method to classify proteins of a family based on their conserved genomic contexts. Each protein genomic context is compared against all others to determine syntenies. A graph is generated where nodes are input proteins connected by edges
Mots-clefs : pangénome ; microbiologie environnementale ; évolution des génomes ; contexte génomique ; graphes La pangénomique vise à comprendre la variabilité génétique d’un groupe d’organismes, généralement d’une même espèce, en agrégeant l’information issue de l’ensemble des génomes disponibles plutôt que
Over the past two decades, MicroScope has been a leading platform empowering microbiologists with powerful tools and resources to delve deep into the fascinating world of microbial genomics. To celebrate this milestone, we invite you to join us at the Genopole