The MicroScope platform is an integrative resource that supports systematic and efficient revision of microbial genome annotation, data management and comparative analysis. Starting from the results of our syntactic, functional and relational annotation pipelines, MicroScope provides an integrated environment for the expert annotation and comparative analysis of prokaryotic genomes. It combines tools and graphical interfaces to analyze genomes and to perform the manual curation of gene function in a comparative genomics and metabolic context. The resource provides data from completed and ongoing genome projects together with post-genomic experiments (i.e. transcriptomics, re-sequencing of evolved strains, mutant collections) allowing users to improve the understanding of gene functions.
The MicroScope platform is constantly evolving both in terms of data content and of new analysis tools some of them being developed in the context of our research projects.
Last news about MicroScope:
Dear MicroScope users, You may have noticed an unusual number of problems in some tools recently (generally ending with a big red error message). This is due to an update in our SQL server that turned on a more strict mode hence some queries are now rejected (despite the results ...
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The version v3.15.3 of the platform is now deployed: As mentioned in the last newsletter, you will be asked to update your personal information when upon login. Moreover you will be asked to update those information every year (see the Privacy Notice for more information). Note that the list of ...
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Dear MicroScope users, MicroScope will be off-line from Friday December 17th 12pm CEST to Monday December 20th around 2pm CEST. This long shut-down is needed to update several components of our IT infrastructure. Services opened the week before might take a little longer than usual to deliver but should stay ...
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In the spring of 2020, we conducted a satisfaction survey with over 1700 users of the MicroScope platform. With this survey we wanted to know more about the profile of our user community and their use of the platform for their current/future projects. You can find some statistics on the ...
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In order to improve the selection of genomes, MicroScope 3.15.2 introduced the possibility to select genomes based on a subset of species-level metadata published in Joshua S. Madin et al., A synthesis of bacterial and archaeal phenotypic trait data. Sci Data 7, 170 (2020). This article unifies phenotypic and quantitative ...
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In order to improve the processing time of the genome analysis, we chose to replace NCBI blast with Diamond version 2 to perform protein sequence alignments (i.e. synteny computations and alignments against UniProt). Internal tests showed that the results obtained were very similar to those of Blast using the "more-sensitive" ...
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We are pleased to inform you about MicroScope professional training courses in 2022. Two sessions of the «Annotation and analysis of prokaryotic genomes using the MicroScope platform» course are planned at the University of Evry: Monday 14th March 2022 – Friday 18th March 2022Monday 21st November 2022 – Friday 25th ...
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Dear MicroScope users, Due to a maintenance operation on several servers at Genoscope, MicroScope will be offline from Friday November 19th afternoon (5 pm CEST time) to Sunday November 21st (the precise time is not known yet). We apologize for any inconvenience,The LABGeM team ...
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Dear MicroScope Users, We recently discovered that some gene fissions (shown on the Gene Fusion/Fission page) were not detected correctly: in some cases, when the gene is split in several parts, only one correspondence is displayed. Note that gene fusions are not affected. We have corrected the bug and updated ...
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Dear MicroScope users, Due to a maintenance operation MicroScope will be offline for few hours on Thursday August 17th from 02:00PM CEST. We apologize for any inconvenience,The LABGeM team ...
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