Laboratory of Bioinformatics Analyses for Genomics and Metabolism
MUDIS4LS project (ESR+/EquipEx PIA3) is leaded by the French Institute of Bioinformatics (IFB). It is based on 4 technological workpackages and 5 thematic projects (Implementation Studies). It gathers 39 teams from 14 organisations, 4 national data centers, 7 regional data
Funded by the French Priority Plan on antibioresistance, the ABRomics project aims at developing an online community-driven platform to scale up and improve surveillance and research on antibiotic resistance from a One Health perspective. The platform is made of: In
PPanGGOLiN (Gautreau et al. 2020) is a software suite used to create and manipulate prokaryotic pangenomes from a set of either genomic DNA sequences or provided genome annotations. It is designed to scale up to tens of thousands of genomes.
Background Today, thanks to the development of metagenomics, our knowledge of microbial diversity has greatly changed. Whereas previously cellular organisms were seen more as independent entities, today we know that they organize themselves into complex microbial communities made up of
Many comparative genomic studies try to get a grasp on the overall gene content of a species. However, with the current explosion of available genomic data, it becomes more complex to use all-vs-all genome comparison approaches. Over the last years,
Eddy Elisée had the honor of being interviewed by the TV program l’esprit sorcier as part of the MODAMDH project, which is being carried out in collaboration between the LCOB and LABGEM. The film can be viewed here : https://www.youtube.com/watch?v=KOU4pRxS9Wc
Mots-clefs : pangénome ; microbiologie environnementale ; évolution des génomes ; contexte génomique ; graphes La pangénomique vise à comprendre la variabilité génétique d’un groupe d’organismes, généralement d’une même espèce, en agrégeant l’information issue de l’ensemble des génomes disponibles plutôt que