Laboratory of Bioinformatics Analyses for Genomics and Metabolism
The aim of this PhD thesis is to achieve new methodological developments for the comparative study of pangenomes. This will involve the development of new bioinformatic methods for inter-pangenome comparisons, which will be particularly based on the developments carried out
PPanGGOLiN (Gautreau et al. 2020) is a software suite used to create and manipulate prokaryotic pangenomes from a set of either genomic DNA sequences or provided genome annotations. It is designed to scale up to tens of thousands of genomes.
Eddy Elisée had the honor of being interviewed by the TV program l’esprit sorcier as part of the MODAMDH project, which is being carried out in collaboration between the LCOB and LABGEM. The film can be viewed here : https://www.youtube.com/watch?v=KOU4pRxS9Wc
Mots-clefs : pangénome ; microbiologie environnementale ; évolution des génomes ; contexte génomique ; graphes La pangénomique vise à comprendre la variabilité génétique d’un groupe d’organismes, généralement d’une même espèce, en agrégeant l’information issue de l’ensemble des génomes disponibles plutôt que