Laboratory of Bioinformatics Analyses for Genomics and Metabolism
One consequence of increasing sequencing capacity is the the accumulation of \textit{in silico} predictions in biological sequence databanks. This amount of data exceeds human curation capacity and, despite methodological progress, numerous errors on the prediction of protein functions are made.
GROOLS (Genomic Rule Oriented Object Logic System) is a bioinformatics software that helps biologists in the evaluation of genome functional annotation through biological processes like metabolic pathways. GROOLS is an expert system that uses paraconsistent logic. It evaluates the completeness
Eddy Elisée had the honor of being interviewed by the TV program l’esprit sorcier as part of the MODAMDH project, which is being carried out in collaboration between the LCOB and LABGEM. The film can be viewed here : https://www.youtube.com/watch?v=KOU4pRxS9Wc
Mots-clefs : pangénome ; microbiologie environnementale ; évolution des génomes ; contexte génomique ; graphes La pangénomique vise à comprendre la variabilité génétique d’un groupe d’organismes, généralement d’une même espèce, en agrégeant l’information issue de l’ensemble des génomes disponibles plutôt que