Laboratory of Bioinformatics Analyses for Genomics and Metabolism
Mots-clefs : pangénome ; microbiologie environnementale ; évolution des génomes ; contexte génomique ; graphes La pangénomique vise à comprendre la variabilité génétique d’un groupe d’organismes, généralement d’une même espèce, en agrégeant l’information issue de l’ensemble des génomes disponibles plutôt que
Funded by the French Priority Plan on antibioresistance, the ABRomics project aims at developing an online community-driven platform to scale up and improve surveillance and research on antibiotic resistance from a One Health perspective. The platform is made of: In
The aim of this PhD thesis is to achieve new methodological developments for the comparative study of pangenomes. This will involve the development of new bioinformatic methods for inter-pangenome comparisons, which will be particularly based on the developments carried out
PPanGGOLiN (Gautreau et al. 2020) is a software suite used to create and manipulate prokaryotic pangenomes from a set of either genomic DNA sequences or provided genome annotations. It is designed to scale up to tens of thousands of genomes.
Horizontal gene transfer (HGT) is a major source of variability in prokaryotic genomes. Regions of Genome Plasticity (RGPs) are clusters of genes located in highly variable genomic regions. Most of them arise from HGT and correspond to Genomic Islands (GIs).
Mots-clefs : pangénome ; microbiologie environnementale ; évolution des génomes ; contexte génomique ; graphes La pangénomique vise à comprendre la variabilité génétique d’un groupe d’organismes, généralement d’une même espèce, en agrégeant l’information issue de l’ensemble des génomes disponibles plutôt que
Over the past two decades, MicroScope has been a leading platform empowering microbiologists with powerful tools and resources to delve deep into the fascinating world of microbial genomics. To celebrate this milestone, we invite you to join us at the Genopole