Laboratory of Bioinformatics Analyses for Genomics and Metabolism
Abstract The emergence of eukaryotes (eukaryogenesis) is one of the central, extensively debated and yet unanswered questions in biology. It was proposed that informational genes as well as cytoskeleton and membrane remodelling/cell division machineries of eukaryotes have been inherited from
Abstract The project focuses on a poorly known carbon-sequestering environmental process by a group of diverse bacteria forming intracellular carbonates, occurring at oxic/anoxic boundaries (OAB) in aquatic environments. The molecular and geochemical processes of bacterial biomineralization will be studied by
Abstract The project aims to decipher the biodiversity, ecology and evolution of a group of unicellular eukaryotes ubiquitous in marine anoxic sediments that sense the Earth’s magnetic field thanks to their symbiotic bacteria. This exploration will be done with a combination of
Background Today, thanks to the development of metagenomics, our knowledge of microbial diversity has greatly changed. Whereas previously cellular organisms were seen more as independent entities, today we know that they organize themselves into complex microbial communities made up of
Description Contexte scientifique : Les Thermococcales sont un ordre d’archées anaérobies et hyperthermophiles, qui vivent au niveau des cheminées océaniques hydrothermales et au niveau de sources chaudes terrestres à pH neutre 1–3. Elles sont utilisées comme organisme modèle pour l’étude
Prokaryotes —bacteria and archaea— are diverse, ubiquitous organisms with vast impacts on health, soil, and ocean ecosystems. Large-scale genome sequencing and pangenomics have revealed their molecular diversity, especially the role of Mobile Genetic Elements (MGEs). Pangenomics analyzes genetic variability across
Localisé au CEA/Genoscope, un centre de recherche scientifique dédié à la génomique environnementale, le Laboratoire d’Analyses Bioinformatiques pour la Génomique et le Métabolisme (LABGeM, UMR8030, labgem.genoscope.cns.fr) s’intéresse à l’analyse et à l’exploration de la diversité des microorganismes et de leur