CRISPRCasFinder predictions in MicroScope

CRISPR (clustered regularly interspaced short palindromic repeats) arrays and their associated (Cas) proteins confer bacteria and archaea adaptive immunity against exogenous mobile genetic elements, such as phages or plasmids. CRISPRCasFinder [1] allows the identification of both CRISPR arrays and Cas proteins (identified by MacSyFinder). 

The list of predicted systems in a selected strain can be accessed through the ‘Macromolecular Systems’ section of the ‘Comparative Genomics’ menu. A new CRISPR table displays all CRISPR detected by CRISPRCasFinder and all Cas detected by MacSyFinder.

Reference:

[1] Couvin D, et al. CRISPRCasFinder, an update of CRISRFinder, includes a portable version, enhanced performance and integrates search for Cas proteins. Nucleic Acids Res. 2018 Jul 2;46(W1):W246-W251.

CRISPRCasFinder predictions in MicroScope