In order to improve the processing time of the genome analysis, we chose to replace NCBI blast with Diamond version 2 to perform protein sequence alignments (i.e. synteny computations and alignments against UniProt). Internal tests showed that the results obtained were very similar to those of Blast using the “more-sensitive” option of Diamond.
Thus, since November 2020, the processing time for the integration of new batches of genomes has been significantly improved to about 2 weeks instead of 4 weeks.
Faster integration for new genomes